Vaccine Structure Visualization
| Element | Description | Position |
|---|---|---|
| cap | A modified 5’-cap1 structure (m7G+m3'-5'-ppp-5'-Am). | 1-2 |
| 5’-UTR | 5´-untranslated region derived from human alpha-globin RNA with an optimized Kozak sequence. | 3-54 |
| sig | S glycoprotein signal peptide (extended leader sequence), which guides translocation of the nascent polypeptide chain into the endoplasmic reticulum. | 55-102 |
| S protein_mut | Codon-optimized sequence encoding full-length SARS-CoV-2 spike (S) glycoprotein containing mutations K986P and V987P to ensure the S glycoprotein remains in an antigenically optimal pre-fusion conformation; stop codons: 3874-3879 (underlined). | 103-3879 |
| 3’-UTR | The 3´ untranslated region comprises two sequence elements derived from the amino-terminal enhancer of split (AES) mRNA and the mitochondrial encoded 12S ribosomal RNA to confer RNA stability and high total protein expression. | 3880-4174 |
| poly(A) | A 110-nucleotide poly(A)-tail consisting of a stretch of 30 adenosine residues, followed by a 10-nucleotide linker sequence and another 70 adenosine residues. | 4175-4284 |
Squiggle Visualization
Mapping: A -> 10, G -> 11, C -> 01, Ψ -> 00
Yau Visualization
Gates Visualization
Images
Source: https://mednet-communities.net/inn/db/media/docs/11889.doc
Sequence
GAGAAΨAAACΨAGΨAΨΨCΨΨCΨGGΨCCCCACAGACΨCAGAGAGAACCCGCCACCAΨGΨΨCGΨGΨΨCCΨGGΨGCΨGCΨGCCΨCΨGGΨGΨCCAGCCAGΨGΨGΨGAACCΨGACCACCAGAACACAGCΨGCCΨCCAGCCΨACACCAACAGCΨΨΨACCAGAGGCGΨGΨACΨACCCCGACAAGGΨGΨΨCAGAΨCCAGCGΨGCΨGCACΨCΨACCCAGGACCΨGΨΨCCΨGCCΨΨΨCΨΨCAGCAACGΨGACCΨGGΨΨCCACGCCAΨCCACGΨGΨCCGGCACCAAΨGGCACCAAGAGAΨΨCGACAACCCCGΨGCΨGCCCΨΨCAACGACGGGGΨGΨACΨΨΨGCCAGCACCGAGAAGΨCCAACAΨCAΨCAGAGGCΨGGAΨCΨΨCGGCACCACACΨGGACAGCAAGACCCAGAGCCΨGCΨGAΨCGΨGAACAACGCCACCAACGΨGGΨCAΨCAAAGΨGΨGCGAGΨΨCCAGΨΨCΨGCAACGACCCCΨΨCCΨGGGCGΨCΨACΨACCACAAGAACAACAAGAGCΨGGAΨGGAAAGCGAGΨΨCCGGGΨGΨACAGCAGCGCCAACAACΨGCACCΨΨCGAGΨACGΨGΨCCCAGCCΨΨΨCCΨGAΨGGACCΨGGAAGGCAAGCAGGGCAACΨΨCAAGAACCΨGCGCGAGΨΨCGΨGΨΨΨAAGAACAΨCGACGGCΨACΨΨCAAGAΨCΨACAGCAAGCACACCCCΨAΨCAACCΨCGΨGCGGGAΨCΨGCCΨCAGGGCΨΨCΨCΨGCΨCΨGGAACCCCΨGGΨGGAΨCΨGCCCAΨCGGCAΨCAACAΨCACCCGGΨΨΨCAGACACΨGCΨGGCCCΨGCACAGAAGCΨACCΨGACACCΨGGCGAΨAGCAGCAGCGGAΨGGACAGCΨGGΨGCCGCCGCΨΨACΨAΨGΨGGGCΨACCΨGCAGCCΨAGAACCΨΨCCΨGCΨGAAGΨACAACGAGAACGGCACCAΨCACCGACGCCGΨGGAΨΨGΨGCΨCΨGGAΨCCΨCΨGAGCGAGACAAAGΨGCACCCΨGAAGΨCCΨΨCACCGΨGGAAAAGGGCAΨCΨACCAGACCAGCAACΨΨCCGGGΨGCAGCCCACCGAAΨCCAΨCGΨGCGGΨΨCCCCAAΨAΨCACCAAΨCΨGΨGCCCCΨΨCGGCGAGGΨGΨΨCAAΨGCCACCAGAΨΨCGCCΨCΨGΨGΨACGCCΨGGAACCGGAAGCGGAΨCAGCAAΨΨGCGΨGGCCGACΨACΨCCGΨGCΨGΨACAACΨCCGCCAGCΨΨCAGCACCΨΨCAAGΨGCΨACGGCGΨGΨCCCCΨACCAAGCΨGAACGACCΨGΨGCΨΨCACAAACGΨGΨACGCCGACAGCΨΨCGΨGAΨCCGGGGAGAΨGAAGΨGCGGCAGAΨΨGCCCCΨGGACAGACAGGCAAGAΨCGCCGACΨACAACΨACAAGCΨGCCCGACGACΨΨCACCGGCΨGΨGΨGAΨΨGCCΨGGAACAGCAACAACCΨGGACΨCCAAAGΨCGGCGGCAACΨACAAΨΨACCΨGΨACCGGCΨGΨΨCCGGAAGΨCCAAΨCΨGAAGCCCΨΨCGAGCGGGACAΨCΨCCACCGAGAΨCΨAΨCAGGCCGGCAGCACCCCΨΨGΨAACGGCGΨGGAAGGCΨΨCAACΨGCΨACΨΨCCCACΨGCAGΨCCΨACGGCΨΨΨCAGCCCACAAAΨGGCGΨGGGCΨAΨCAGCCCΨACAGAGΨGGΨGGΨGCΨGAGCΨΨCGAACΨGCΨGCAΨGCCCCΨGCCACAGΨGΨGCGGCCCΨAAGAAAAGCACCAAΨCΨCGΨGAAGAACAAAΨGCGΨGAACΨΨCAACΨΨCAACGGCCΨGACCGGCACCGGCGΨGCΨGACAGAGAGCAACAAGAAGΨΨCCΨGCCAΨΨCCAGCAGΨΨΨGGCCGGGAΨAΨCGCCGAΨACCACAGACGCCGΨΨAGAGAΨCCCCAGACACΨGGAAAΨCCΨGGACAΨCACCCCΨΨGCAGCΨΨCGGCGGAGΨGΨCΨGΨGAΨCACCCCΨGGCACCAACACCAGCAAΨCAGGΨGGCAGΨGCΨGΨACCAGGACGΨGAACΨGΨACCGAAGΨGCCCGΨGGCCAΨΨCACGCCGAΨCAGCΨGACACCΨACAΨGGCGGGΨGΨACΨCCACCGGCAGCAAΨGΨGΨΨΨCAGACCAGAGCCGGCΨGΨCΨGAΨCGGAGCCGAGCACGΨGAACAAΨAGCΨACGAGΨGCGACAΨCCCCAΨCGGCGCΨGGAAΨCΨGCGCCAGCΨACCAGACACAGACAAACAGCCCΨCGGAGAGCCAGAAGCGΨGGCCAGCCAGAGCAΨCAΨΨGCCΨACACAAΨGΨCΨCΨGGGCGCCGAGAACAGCGΨGGCCΨACΨCCAACAACΨCΨAΨCGCΨAΨCCCCACCAACΨΨCACCAΨCAGCGΨGACCACAGAGAΨCCΨGCCΨGΨGΨCCAΨGACCAAGACCAGCGΨGGACΨGCACCAΨGΨACAΨCΨGCGGCGAΨΨCCACCGAGΨGCΨCCAACCΨGCΨGCΨGCAGΨACGGCAGCΨΨCΨGCACCCAGCΨGAAΨAGAGCCCΨGACAGGGAΨCGCCGΨGGAACAGGACAAGAACACCCAAGAGGΨGΨΨCGCCCAAGΨGAAGCAGAΨCΨACAAGACCCCΨCCΨAΨCAAGGACΨΨCGGCGGCΨΨCAAΨΨΨCAGCCAGAΨΨCΨGCCCGAΨCCΨAGCAAGCCCAGCAAGCGGAGCΨΨCAΨCGAGGACCΨGCΨGΨΨCAACAAAGΨGACACΨGGCCGACGCCGGCΨΨCAΨCAAGCAGΨAΨGGCGAΨΨGΨCΨGGGCGACAΨΨGCCGCCAGGGAΨCΨGAΨΨΨGCGCCCAGAAGΨΨΨAACGGACΨGACAGΨGCΨGCCΨCCΨCΨGCΨGACCGAΨGAGAΨGAΨCGCCCAGΨACACAΨCΨGCCCΨGCΨGGCCGGCACAAΨCACAAGCGGCΨGGACAΨΨΨGGAGCAGGCGCCGCΨCΨGCAGAΨCCCCΨΨΨGCΨAΨGCAGAΨGGCCΨACCGGΨΨCAACGGCAΨCGGAGΨGACCCAGAAΨGΨGCΨGΨACGAGAACCAGAAGCΨGAΨCGCCAACCAGΨΨCAACAGCGCCAΨCGGCAAGAΨCCAGGACAGCCΨGAGCAGCACAGCAAGCGCCCΨGGGAAAGCΨGCAGGACGΨGGΨCAACCAGAAΨGCCCAGGCACΨGAACACCCΨGGΨCAAGCAGCΨGΨCCΨCCAACΨΨCGGCGCCAΨCAGCΨCΨGΨGCΨGAACGAΨAΨCCΨGAGCAGACΨGGACCCΨCCΨGAGGCCGAGGΨGCAGAΨCGACAGACΨGAΨCACAGGCAGACΨGCAGAGCCΨCCAGACAΨACGΨGACCCAGCAGCΨGAΨCAGAGCCGCCGAGAΨΨAGAGCCΨCΨGCCAAΨCΨGGCCGCCACCAAGAΨGΨCΨGAGΨGΨGΨGCΨGGGCCAGAGCAAGAGAGΨGGACΨΨΨΨGCGGCAAGGGCΨACCACCΨGAΨGAGCΨΨCCCΨCAGΨCΨGCCCCΨCACGGCGΨGGΨGΨΨΨCΨGCACGΨGACAΨAΨGΨGCCCGCΨCAAGAGAAGAAΨΨΨCACCACCGCΨCCAGCCAΨCΨGCCACGACGGCAAAGCCCACΨΨΨCCΨAGAGAAGGCGΨGΨΨCGΨGΨCCAACGGCACCCAΨΨGGΨΨCGΨGACACAGCGGAACΨΨCΨACGAGCCCCAGAΨCAΨCACCACCGACAACACCΨΨCGΨGΨCΨGGCAACΨGCGACGΨCGΨGAΨCGGCAΨΨGΨGAACAAΨACCGΨGΨACGACCCΨCΨGCAGCCCGAGCΨGGACAGCΨΨCAAAGAGGAACΨGGACAAGΨACΨΨΨAAGAACCACACAAGCCCCGACGΨGGACCΨGGGCGAΨAΨCAGCGGAAΨCAAΨGCCAGCGΨCGΨGAACAΨCCAGAAAGAGAΨCGACCGGCΨGAACGAGGΨGGCCAAGAAΨCΨGAACGAGAGCCΨGAΨCGACCΨGCAAGAACΨGGGGAAGΨACGAGCAGΨACAΨCAAGΨGGCCCΨGGΨACAΨCΨGGCΨGGGCΨΨΨAΨCGCCGGACΨGAΨΨGCCAΨCGΨGAΨGGΨCACAAΨCAΨGCΨGΨGΨΨGCAΨGACCAGCΨGCΨGΨAGCΨGCCΨGAAGGGCΨGΨΨGΨAGCΨGΨGGCAGCΨGCΨGCAAGΨΨCGACGAGGACGAΨΨCΨGAGCCCGΨGCΨGAAGGGCGΨGAAACΨGCACΨACACAΨGAΨGACΨCGAGCΨGGΨACΨGCAΨGCACGCAAΨGCΨAGCΨGCCCCΨΨΨCCCGΨCCΨGGGΨACCCCGAGΨCΨCCCCCGACCΨCGGGΨCCCAGGΨAΨGCΨCCCACCΨCCACCΨGCCCCACΨCACCACCΨCΨGCΨAGΨΨCCAGACACCΨCCCAAGCACGCAGCAAΨGCAGCΨCAAAACGCΨΨAGCCΨAGCCACACCCCCACGGGAAACAGCAGΨGAΨΨAACCΨΨΨAGCAAΨAAACGAAAGΨΨΨAACΨAAGCΨAΨACΨAACCCCAGGGΨΨGGΨCAAΨΨΨCGΨGCCAGCCACACCCΨGGAGCΨAGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAGCAΨAΨGACΨAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA